Alternative Splicing & Disease (Genetics - Research and Issues)

By Brand : Elias Massey

Mrp Price :

Price : Price

22549

You Save :

Avg Customer Reviews :

Product Features :

Alternative splicing (AS) is a fundamental mechanism of gene expression regulation that extremely expands the coding potential of genomes and the cellular transcriptomic and proteomic diversity. This dynamic and finely-tuned machinery is particularly widespread in the nervous system and is critical for both neuronal development and functions. Alternative splicing defects, therefore, frequently underlie neurological disorders. In the first chapter of this book, the authors focus on Parkinson's disease (PD), the second most common neurodegenerative disorder worldwide. They provide a current overview on the impact of alternative splicing in PD by representing the multiple splicing transcripts produced from the major PD-linked genes and their regulation in PD states; review the studies describing global splicing expression changes revealed by whole-genome transcriptomic approaches; and summarise the current knowledge about the alternative splicing modulation in PD through non-coding RNAs (miRNA and lcnRNA) molecules. The following chapter reviews tau alternative splicing in Alzheimer's disease. Chapter three examines the role of splicing factors in cancer prognosis and treatment. The last chapter studies nonsense-mediated decay and human disease.

Compare With Similar Items

by Charlotte J Sumner

Spinal Muscular Atrophy: Disease Mechanisms and Therapy

Price:

10638

You Save:

by Ineta Vilumsone-Nemes

Industrial Cutting of Textile Materials (The Textile Institute Book Series)

Price:

15755

18090

You Save:

2335

by Yun Q. Shi

Digital-Forensics and Watermarking: 11th International Workshop, IWDW 2012, Shanghai, China, October 31--November 3, 2012, Revised Selected Papers: 7809 (Lecture Notes in Computer Science)

Price:

6461

You Save:

If you have a business establishment in india,

Contact us

to list your business related to any construction categories.

Browse by Topic

Paints, Varnishes And Distermpers

Steel

Construction Events

To Know more about the events about Air Conditioners, Basements, Bathrooms, Bedrooms, Cabinets, Decorating, Design Plans, Doors, Electrical Lightings, Flooring, Home Security, Kitchen, Landscape, Painting, Plumbing, Fixtures and many more..

Read More..